Gene information
Official symbol MIR16-1
Official full name microRNA 16-1
Gene type microRNA
Chromosome13q14.2
Alias symbolhsa-mir-16-1
Previous symbolMIRN16-1
Gene familyMicroRNA MIR15/16 family
Resources
Entrez Gene 406950
HGNC HGNC:31545
Ensembl ENSG00000208006
UCSC uc001vea.2
GO terms: 117 records
GO Description Category LogP Number of genes Detail
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001678 cellular glucose homeostasis GO Biological Processes -13.5994972 27 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001936 regulation of endothelial cell proliferation GO Biological Processes -54.5504306 75 More
GO:0001937 negative regulation of endothelial cell proliferation GO Biological Processes -27.2173755 21 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0002009 morphogenesis of an epithelium GO Biological Processes -21.4354199 71 More
GO:0003729 mRNA binding GO Molecular Functions -83.3296105 82 More
GO:0003730 mRNA 3'-UTR binding GO Molecular Functions -66.9774057 54 More
GO:0006417 regulation of translation GO Biological Processes -24.5257987 35 More
GO:0007346 regulation of mitotic cell cycle GO Biological Processes -10.6017433 22 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0009743 response to carbohydrate GO Biological Processes -20.6536066 44 More
GO:0009746 response to hexose GO Biological Processes -16.2230361 35 More
GO:0009749 response to glucose GO Biological Processes -15.7538948 34 More
GO:0010564 regulation of cell cycle process GO Biological Processes -6.45429517 20 More
GO:0010574 regulation of vascular endothelial growth factor production GO Biological Processes -24.2705452 18 More
GO:0010594 regulation of endothelial cell migration GO Biological Processes -41.8778170 72 More
GO:0010596 negative regulation of endothelial cell migration GO Biological Processes -31.4991544 25 More
GO:0010632 regulation of epithelial cell migration GO Biological Processes -42.8870194 81 More
GO:0010633 negative regulation of epithelial cell migration GO Biological Processes -29.7632977 25 More
GO:0010660 regulation of muscle cell apoptotic process GO Biological Processes -26.1774267 35 More
GO:0010661 positive regulation of muscle cell apoptotic process GO Biological Processes -13.2907676 16 More
GO:0010662 regulation of striated muscle cell apoptotic process GO Biological Processes -17.3771355 22 More
GO:0010663 positive regulation of striated muscle cell apoptotic process GO Biological Processes -8.14754197 9 More
GO:0010665 regulation of cardiac muscle cell apoptotic process GO Biological Processes -17.8825743 22 More
GO:0010666 positive regulation of cardiac muscle cell apoptotic process GO Biological Processes -8.14754197 9 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0010948 negative regulation of cell cycle process GO Biological Processes -6.78057192 13 More
GO:0016441 post-transcriptional gene silencing GO Biological Processes -100 124 More
GO:0016525 negative regulation of angiogenesis GO Biological Processes -31.9326641 51 More
GO:0017148 negative regulation of translation GO Biological Processes -31.7864246 33 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0030336 negative regulation of cell migration GO Biological Processes -30.9008082 37 More
GO:0030371 translation repressor activity GO Molecular Functions -100 82 More
GO:0031047 gene silencing by RNA GO Biological Processes -100 125 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031348 negative regulation of defense response GO Biological Processes -30.3795513 65 More
GO:0032088 negative regulation of NF-kappaB transcription factor activity GO Biological Processes -5.01152693 15 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0033500 carbohydrate homeostasis GO Biological Processes -23.7918768 50 More
GO:0034103 regulation of tissue remodeling GO Biological Processes -21.5631413 32 More
GO:0034105 positive regulation of tissue remodeling GO Biological Processes -9.72787949 7 More
GO:0034248 regulation of cellular amide metabolic process GO Biological Processes -28.1662419 40 More
GO:0034249 negative regulation of cellular amide metabolic process GO Biological Processes -35.7644618 37 More
GO:0034284 response to monosaccharide GO Biological Processes -18.9205843 39 More
GO:0035194 post-transcriptional gene silencing by RNA GO Biological Processes -100 124 More
GO:0035195 miRNA-mediated gene silencing GO Biological Processes -100 124 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035278 miRNA-mediated gene silencing by inhibition of translation GO Biological Processes -46.1099674 32 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway GO Biological Processes -4.66781085 9 More
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway GO Biological Processes -3.41852381 6 More
GO:0042593 glucose homeostasis GO Biological Processes -23.8963802 50 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling GO Biological Processes -3.60984508 9 More
GO:0043433 negative regulation of DNA-binding transcription factor activity GO Biological Processes -10.6964949 32 More
GO:0043535 regulation of blood vessel endothelial cell migration GO Biological Processes -45.8916712 37 More
GO:0043537 negative regulation of blood vessel endothelial cell migration GO Biological Processes -32.3610392 24 More
GO:0045182 translation regulator activity GO Molecular Functions -97.0300828 82 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0045786 negative regulation of cell cycle GO Biological Processes -11.4279863 20 More
GO:0045930 negative regulation of mitotic cell cycle GO Biological Processes -12.1211141 17 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050680 negative regulation of epithelial cell proliferation GO Biological Processes -26.5961536 48 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050728 negative regulation of inflammatory response GO Biological Processes -31.0556128 55 More
GO:0050922 negative regulation of chemotaxis GO Biological Processes -8.57011989 17 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
GO:0051271 negative regulation of cellular component movement GO Biological Processes -29.9238399 37 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0055082 cellular chemical homeostasis GO Biological Processes -17.6289728 71 More
GO:0060562 epithelial tube morphogenesis GO Biological Processes -17.7630248 53 More
GO:0071322 cellular response to carbohydrate stimulus GO Biological Processes -12.8816523 25 More
GO:0071326 cellular response to monosaccharide stimulus GO Biological Processes -13.2453179 24 More
GO:0071331 cellular response to hexose stimulus GO Biological Processes -12.5306046 23 More
GO:0071333 cellular response to glucose stimulus GO Biological Processes -12.7795214 23 More
GO:0072091 regulation of stem cell proliferation GO Biological Processes -6.89052200 13 More
GO:0090049 regulation of cell migration involved in sprouting angiogenesis GO Biological Processes -34.2220297 25 More
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis GO Biological Processes -23.4562080 16 More
GO:0090287 regulation of cellular response to growth factor stimulus GO Biological Processes -21.1381780 60 More
GO:0090288 negative regulation of cellular response to growth factor stimulus GO Biological Processes -9.39414218 23 More
GO:1900015 regulation of cytokine production involved in inflammatory response GO Biological Processes -18.8349263 16 More
GO:1900016 negative regulation of cytokine production involved in inflammatory response GO Biological Processes -7.97228906 7 More
GO:1900746 regulation of vascular endothelial growth factor signaling pathway GO Biological Processes -8.31468142 11 More
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway GO Biological Processes -4.51852976 6 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901343 negative regulation of vasculature development GO Biological Processes -32.5354692 52 More
GO:1901987 regulation of cell cycle phase transition GO Biological Processes -7.48321149 17 More
GO:1901988 negative regulation of cell cycle phase transition GO Biological Processes -6.79968458 12 More
GO:1901990 regulation of mitotic cell cycle phase transition GO Biological Processes -9.06841215 17 More
GO:1901991 negative regulation of mitotic cell cycle phase transition GO Biological Processes -8.19381421 12 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus GO Biological Processes -7.92453051 11 More
GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus GO Biological Processes -4.18483678 6 More
GO:1902806 regulation of cell cycle G1/S phase transition GO Biological Processes -9.32363308 14 More
GO:1902807 negative regulation of cell cycle G1/S phase transition GO Biological Processes -8.70120563 10 More
GO:1903231 mRNA base-pairing post-transcriptional repressor activity GO Molecular Functions -100 82 More
GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO Biological Processes -28.1722563 19 More
GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO Biological Processes -14.8848049 10 More
GO:1904046 negative regulation of vascular endothelial growth factor production GO Biological Processes -20.8132034 13 More
GO:1904847 regulation of cell chemotaxis to fibroblast growth factor GO Biological Processes -4.24949804 3 More
GO:1904848 negative regulation of cell chemotaxis to fibroblast growth factor GO Biological Processes -5.45324468 3 More
GO:2000045 regulation of G1/S transition of mitotic cell cycle GO Biological Processes -10.1341432 14 More
GO:2000112 regulation of cellular macromolecule biosynthetic process GO Biological Processes -24.0725356 37 More
GO:2000113 negative regulation of cellular macromolecule biosynthetic process GO Biological Processes -32.997895 35 More
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle GO Biological Processes -9.22212459 10 More
GO:2000146 negative regulation of cell motility GO Biological Processes -30.256132 37 More
GO:2000181 negative regulation of blood vessel morphogenesis GO Biological Processes -32.6997315 52 More
GO:2000241 regulation of reproductive process GO Biological Processes -4.23306387 21 More
GO:2000647 negative regulation of stem cell proliferation GO Biological Processes -4.56141436 5 More
GO:2001026 regulation of endothelial cell chemotaxis GO Biological Processes -8.98205881 11 More
GO:2001027 negative regulation of endothelial cell chemotaxis GO Biological Processes -4.91375876 3 More
GO:2001235 positive regulation of apoptotic signaling pathway GO Biological Processes -13.4065813 30 More
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway GO Biological Processes -6.75355964 14 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa05206 MicroRNAs in cancer KEGG Pathway -100 81 More
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
hsa-miR-16-5p transcriptomics left ventricular dysfunction[prognosis (bad)] acute myocardial infarction Devaux Y et al. PLoS One. 2013
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